| Title | Publisher | Year | Language | Documents |
|---|---|---|---|---|
| Edgar's Adventures | SoftDisk | 1996 | English | |
| Egypt Adventure | K-Soft |
1993 | Czech | |
| Eleusinian Miseries, The | Mike Russo | 2020 | English | |
| Elizabeth Hawke's Forever Always | Iain Merrick | 2002 | English | |
| Epidémie | Froggy Software | 1984 | French | |
| Episode in the Life of an Artist | Peter Eastman | 2003 | English | Solution |
| Eric the Unready | Legend Entertainment |
1991 | English | Solution |
| Exactly 14 syllables... er, gulps! | Valentine Kopteltsev | 2013 | English | |
| Examen, El | Burga's Adventure | 1989 | Spanish | Solution |
| Expreso de los Vampiros, El | Indiana K. Jones | 2011 | Spanish |